The Indianapolis Colts are being watched as one of the NFL's most active sellers heading into the Nov. 10 trade deadline, four days after owner Carlie Irsay-Gordon fired longtime general manager Chris Ballard following a 26-20 home loss to the rival Tennessee Titans that dropped the team to 2-4.

Ballard's nine-year tenure ends with a 72-82-1 record and two playoff appearances. Assistant general manager Ed Dodds is expected to run personnel decisions on an interim basis for the rest of the season, and Newsweek reported that multiple Colts Pro Bowlers could now be in play as the front office reassesses the roster.

Nelson at the center of it

ESPN's Jordan Reid has identified left guard Quenton Nelson, a six-time Pro Bowler and one of the most respected offensive linemen of his generation, as the player likely to generate the most interest around the league. Nelson, 30, is on an expiring contract, and extension talks have not progressed, according to multiple reports. Fox Sports separately named him the Colts' top trade candidate for the same reason: a star player on a short-term deal with a rebuilding team that could extract real value for him rather than let him walk as a free agent.

A FIRE SALE COULD BE ON THE TABLE FOR A TEAM THAT JUST FIRED THE MAN WHO BUILT MOST OF ITS ROSTER

Other names being floated as potential trade chips include All-Pro defensive tackle DeForest Buckner and running back Jonathan Taylor, though neither is considered as likely to move as Nelson. Because Indianapolis already dealt away a 2027 first-round pick in an earlier trade for cornerback Sauce Gardner, interim leadership is expected to prioritize adding draft capital in any deal it makes.

A broader shakeup

The firing has also raised questions about head coach Shane Steichen's job security, with reporting describing his future in Indianapolis as uncertain depending on how the rest of the season unfolds. The Colts' collapse comes one season after a surprise playoff run, underscoring how quickly fortunes can turn in a league with little roster continuity once a front office changes hands mid-season.

Across the rest of the NFL, the deadline is shaping up as an active one more broadly: NFL.com's trade-deadline coverage floated moves involving Saquon Barkley, Trey Hendrickson and Jonathan Taylor among the names in play, and ESPN's Adam Schefter said Thursday that the Philadelphia Eagles could end up as both buyers and sellers depending on how their season trends over the next two weeks.

What's next

Teams have until 4 p.m. ET on Nov. 10 to complete trades. With the Colts now operating without the general manager who assembled most of their current roster, rival executives expect Indianapolis to be one of the more unpredictable teams on the board between now and the deadline.