Prostate cancer is more aggressive for smokers

Men who suffer from prostate cancer and are smokers are more likely to experience tumor recurrence, their metastases to other parts of the body and premature death than those who do not smoke, according to a new international scientific study.

The researchers, led by Dr. Sarah Sariat of the Department of Urology at the Medical University of Vienna, who published the relevant publication in the American Journal of Oncology “JAMA Oncology”, according to Reuters, evaluated previous research findings, which involved a total of 22,549 men with non-metastatic prostate cancer who had either removed tumors or radiotherapy.

Nearly one in five patients were smokers, while the other ex-smokers. The cancer patients were followed for six to eight years, during which they died of 8%.

On average, as meta-analysis showed, smokers were 40% more likely to develop tumors after treatment and had more than twice as much risk of metastases beyond the prostate. Smokers were also 89% more likely to die from cancer.

Ex-smokers had a higher risk of tumor recurrence, but not metastases or premature death. “This shows the importance of smoking for the progression of the disease,” said Sarayt, pointing out that “the men who had cut the cigarette for more than ten years did not show any significant difference compared to those who had never smoke “.

Smoking is directly associated with an increased risk of death from various cancers (lung, trachea, larynx, stomach, kidney, etc.). It is not yet clear exactly how smoking favors the proliferation of prostate cancer or makes it more aggressive and lethal. One possibility is that smoking causes inflammation that encourages tumor growth and another possible explanation that nicotine itself favors the spread of cancer.