The first non-invasive anti-cancer therapy system that uses ultrasound to remotely control genetic processes within the patient’s immune cells so that they can then better recognize and destroy cancer cells more effectively, developed scientists in the US.
The revolutionary technique is part of the new field of mechanogenetics, namely the use of natural forces to initially alter the mechanical properties of cells and then change the expression of cell genes. In this way, a form of tele-direction of the actions of the cells and their genes is achieved.
In this case, ultrasounds mechanically affect the T lymphocytes of the immune system and then the mechanical signals induced are transformed into genetic control of the cells in order to better fight the cancer.
The researchers, led by the biotechnology professor Peter Wang of the University of California at San Diego, published in the journal of the National Academy of Sciences of the United States (PNAS), genetically modified the T-immune cells they now have the appropriate sensors, which can be remote controlled by ultrasound.