The first trailer for "Trust Me, I'm a Doctor," the long-awaited Anna Nicole Smith biopic, has arrived — and it's already stirring up reactions ahead of its October 16 theatrical release.

Abbie Cornish transforms into the late model and reality star, while Kal Penn plays Dr. Sandeep Kapoor, the physician implicated in Smith's 2007 death, whose memoir the film is based on. Linda Hamilton also stars. TheWrap notes the trailer leans into both the glamour and the tragedy of Smith's final years, teasing a dramatic retelling of one of the 2000s' biggest tabloid sagas.

Cornish's transformation has drawn particular attention, with early images showing her nearly unrecognizable in the role. Not everyone is thrilled about the project, however — Smith's ex Larry Birkhead has voiced concerns about how the film might affect the couple's teenage daughter, Dannielynn. Whether the movie treats its subject with empathy or exploitation will likely be the debate once it hits theaters.