For the first time, scientists developed perfect human blood vessels in the laboratory, making progress in the use of such organoids, as they are called, in the future to treat various vascular diseases in patients like diabetics.
Researchers from Canada, the USA, Austria and the UK, led by Dr. Joseph Penninger, director of the Life Sciences Institute of the University of British Columbia in Vancouver and head of the Institute of Molecular Biotechnology of the Austrian Academy of Sciences, who published in the journal Nature created so-called “vascular organoids” by cultivating human pluripotent stem cells.
Laboratory vessels, mimicking the structure and function of real human blood vessels, were transplanted into mice and functioned as normal organs with their arteries and capillaries.
“The ability to create human blood vessels as organoids from stem cells is a revolutionary change. Because every organ in our body is connected to the circulatory system, researchers can now illuminate the causes and find new therapies for various vascular diseases, such as Alzheimer’s, cardiovascular disease, stroke, cancer and, of course, diabetes. “
Many symptoms of diabetes – of which approximately 420 million people worldwide suffer – are the result of changes in blood vessels, resulting in problems in the bloodstream and in the oxygenation of tissues. Although it is common, very little is known about vascular changes due to diabetes, resulting in the delays in the development of new therapies according to RES-EIA.